Vaccinology Textbooks

Vaccines for Biodefense and Emerging and
Neglected Diseases

Description: The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases", "neglected diseases", and those that are deemed biothreats. It is well recognized that the most effective modality for preventing infectious diseases is vaccination. This book provides researchers with a better understanding of what is currently known about these types of diseases, including whether there is a vaccine available or under development. It also informs readers of the key issues in development of a vaccine for each disease.

• Provides a comprehensive treatise of the agents that are responsible for emerging and neglected diseases and those that can be used as biothreats
• Includes the processes such as the vaccine development pathway, vaccine manufacturing and regulatory issues that are critical to the generation of these vaccines to the marketplace
• Each chapter includes a map of the world showing where that particular disease is naturally found

About the Editors

Drs. Lawrence Stanberry and Alan Barrett, are highly respected authorities in vaccine development. Dr. Barrett researches tropical virus diseases such as dengue, West Nile, yellow fever and Japanese encephalitis. He has made important contributions to molecular aspects of immunogens and preclinical development of candidate vaccines for these diseases, and studies on the current yellow fever 17D vaccine. Dr. Stanberry (the Reuben S. Carpentier Professor and Chairman of the Department of Pediatrics at the College of Physicians and Surgeons at Columbia University, and Pediatrician-in-Chief of New York-Presbyterian Morgan Stanley Children’s Hospital)has made important contributions in the areas of tropical microbicides and in herpes simplex virus pathogenesis, immunobiology and antiviral therapy. He has played major roles in the pre-clinical and clinical assessment of many of the herpes vaccines currently in development.

Do Vaccines Cause That?!
A Guide for Evaluating Vaccine Safety Concerns

Description: Almost 70% of parents who refuse to vaccinate their children believe vaccines may cause harm. Vaccines have been blamed for causing asthma, autism, diabetes, and many other conditions, most of which have causes that are incompletely understood. To respond to these concerns about vaccine safety, the National Network for Immunization Information (NNii) writing team of Dr. Martin G. Myers and Mr. Diego Pineda wrote a book titled, Do Vaccines Cause That?! A Guide for Evaluating Vaccine Safety Concerns. The purpose of the book is to provide parents clearly understandable, science-based information about vaccines, immunization, and vaccine safety and is divided in two sections. The first section tells parents how best to weigh and evaluate what they read or hear about vaccine safety, emphasizing how a scientist determines causality. The second section deals specifically with vaccine safety concerns such as asthma, autism, and autoimmune diseases, among others.

About the Authors

Dr. Martin Myers is an internationally recognized vaccine expert and former director of the National Vaccine Program Office. He is presently Professor Emeritus in the Department of Pediatrics at UTMB. Mr. Diego Pineda has been NNii's science writer since 2004.

Vaccinology: An Essential Guide

Description: Vaccinology: An Essential Guide is a perfect tool designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. In a clear practical format, this book outlines the entire vaccine development process from conceptualization and basic immunological principles through clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterrorism. There are also sections devoted to veterinary vaccines and associated regulatory processes.The book is also suitable for everyone involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.

About the Editors

Drs. Alan Barrett and Gregg Milligan are world-renowned experts in vaccine development and viral immunology. Dr. Barrett, a recognized leader in the biology of flaviviruses, researches tropical virus diseases such as dengue, West Nile, yellow fever and Japanese encephalitis. He has made important contributions to molecular aspects of immunogens and preclinical development of candidate vaccines for these diseases, and studies on the current yellow fever 17D vaccine. Dr. Milligan's research focuses on the innate and adaptive immune responses to herpes viruses. Additionally, he examines the linkage of the innate immune response to vaccines with the development of adaptive immune responses and the role of tissue-resident immune memory cells in protection against virus infections and disease.