Colonoscopy

Early detection and trusted care for your digestive health

Man and woman sitting on couch smiling at each other

Take charge of your colorectal health (to replace Life-saving Screenings)

Colonoscopy services combine advanced technology with a compassionate approach to care. At UTMB Health, our experienced gastroenterology team focuses on your comfort, safety, and peace of mind, helping you take a proactive step toward long-term digestive health. A colonoscopy is one of the most reliable ways to detect and prevent colorectal cancer. Using a thin, flexible scope with a small camera, our specialists carefully examine the lining of your colon and rectum to identify and remove polyps or other abnormal tissue before they become serious concerns.

Preparing for Your Colonoscopy  

Before Your Procedure

  • Diet: Restrict your diet and take your bowel prep medicine to clean out your colon.
  • Medication: You may also need to change your medication routine if you take medicines like aspirin, Plavix®, clopidogrel, anti-inflammatory medicines, blood thinners, diabetes medicine, or fish oil. See the full medication hold list and the colonoscopy prep instructions.
  • Prep medicine: Your doctor needs a clear view inside your colon to perform the test accurately. If your colon isn’t properly cleaned, it can block the view of important findings, such as polyps or signs of cancer. An incomplete view may mean you’ll need to repeat the test.

Think of your colon this way:

  • When it’s clean, it’s like a nice day where you can see for miles.
  • When it’s dirty, it’s like a foggy day. It’s hard to see and hard to drive.
    • Bowel movements: You will experience frequent bowel movements (diarrhea) as a result of the bowel preparation. This typically begins within a few minutes to three hours after starting the prep. Plan to stay home and remain close to a restroom during this time.
    • Symptoms: Most people experience bloating, abdominal discomfort, and nausea. These symptoms are normal. If you have nausea with vomiting, please call one of the numbers below to let your GI doctor know:

Medication Instructions

  • 7 Days Before Procedure
     STOP TAKING
    • Herbal and workout supplements
    • Over the counter medications such as:
      • Fish oil
      • Pain relievers (ex. Aleve, Motrin, Advil, and Ibuprofen, or Aspirin—unless directed otherwise by your surgeon)
    • Oral weight loss medications (ex. Phentermine, Adipex, Fastin)
    • Weekly administered weight loss and diabetic injections: Dulaglutide/Trulicity, Exenatide/Bydureon BCise, Exanatide/Byetta, Semaglutide/Ozempic, Wegovy, Tirzepatide/Mounjaro
     CONTINUE TAKING, as needed
    • Acid reflux medications (ex. Pepcid, Protonix and Prilosec)
    • Tylenol for pain
  • 4 Days Before Procedure
     STOP TAKING
    • SGLT2 inhibitor (Ertugliflozin)
  • 3 Days Before Procedure
     STOP TAKING
    • Certain diabetes medications that end with “gliflozin” (ex. empagliflozin, canagliflozin, and dapagliflozin. Trade names are Invokana, Farxiga, Jardiance, and several others.) Only stop these types of diabetic medicines. Continue all other diabetic medications.
  • 1 Day Before Procedure
     STOP TAKING
    • Long-acting Insulin, take only ½ dose the night before surgery
    • Certain high blood pressure medications called:
      • ACE inhibitors (ex. Benazepril, Captopril, Lisinopril)
      • ARBs (ex. Losartan, Olmesartan, Valsartan)
    • Recreational drugs, alcohol, and tobacco
  • Day of Procedure
     STOP TAKING
    • Insulin
    • Oral diabetic medication
    • Diuretics (aka “water pills”)
    • Fiber or bulking agents
    • Medications that require you to take with food or milk
    • Daily administered weight loss and diabetic medications (oral and injected): Liraglutide/Saxena, Victoza, Lixisenatide/Adlyxin, Semaglutide/Rybelsus, Novo Nordisk
     CONTINUE TAKING, as directed Medications that SHOULD be taken on the day of surgery with a sip of water
    • All other blood pressure medications (excluding those listed above such as ACE Inhibitors and ARB)
    • Asthma Inhalers (bring these with you)
    • Acid reflux medications (ex. Pepcid, Protonix and Prilosec)
    • Clonidine
    • Gabapentin or Lyrica
    • Thyroid medications
    • Regularly scheduled prescribed pain medications such as norco
  • Blood Thinning Medications

    Whether to continue or stop taking your blood thinning/anticoagulant medications is determined by what type of surgery you are having and your surgeon’s preference. You will be instructed by your surgeon regarding stopping blood thinning medications.

Colonoscopy Prep Medicine Instructions

Your doctor will prescribe a specific prep medicine tailored to you.

The Day of Your Procedure

  • Transportation: You must have a responsible adult (18 years or older) bring you to your procedure, stay during your visit, and drive you home afterward:
    • Your driver must be present at check-in.
    • You cannot leave alone or use a taxi, rideshare, or bus for transportation.
    • If you arrive without a responsible adult, your procedure will be rescheduled.
  • Valuables: Don’t bring jewelry, cash, or other valuables to your appointment.
  • Check-in: After registration, you’ll be escorted to the pre-operative area to prepare for your procedure. One visitor may join you once the pre-op area is ready.
  • Procedure duration: Expect to be at the Endoscopy Unit for about 2–4 hours total. The exam itself takes about 30–45 minutes.

After Your Procedure

  • Rest and recovery: After your procedure, you’ll rest in a recovery area until the sedative wears off. You’ll be monitored for a short time before being released to go home. You may feel groggy for a while after your procedure, which is normal.
  • Consultation: Once you’re fully alert, your physician will review your results and next steps with you.
  • Transportation: As a reminder, you must have a responsible person, 18+ years old, drive you home after the procedure if you received anesthesia.
  • Side Effects

    Your procedure itself can cause several side effects, such as:

    • Abdominal cramping
    • Bloating
    • Gas
    • Some slight rectal bleeding

    These side effects are usually mild and go away on their own within a day or two.

    If the bleeding continues or the stool contains a large amount of blood or blood clots, call the Endoscopy main line immediately.

  • At-Home Care
    After your procedure you should be watched by a responsible adult for 8 hours. This is to monitor for any adverse effects of the procedure and medications you were given.
    Don’t drink any alcohol for the next 24 hours
    Don’t drive or operate any dangerous machinery or make important business or personal decisions during the next 24 hours.
  • Follow-Up Care

    Follow up with your healthcare provider as advised. Also follow up with your provider if you are not alert and back to your usual level of activity within 12 hours.

  • When to Seek Medical Advice

    Have someone call your healthcare provider right away if any of these occur:

    • Drowsiness gets worse
    • Weakness or dizziness gets worse
    • Repeated vomiting
    • Severe or ongoing pain from the procedure that’s not eased by the pain medicine (if prescribed)
    • Fever
  • When to Call 911

    Have someone call 911 if you have any of the following.

    • Shortness of breath
    • Chest pain
    • Loss of consciousness or you cannot be awakened

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